萨曼莎（Samantha）在蒙大拿州（Montana）的牧场是她家族的遗产，因此当开发商出现要购买时，萨姆（Sam）对此并不感兴趣。 但是当他试图赢得她的信任和牧场时，山姆发现他也可能赢得了她的心。

加菲猫是一只把所有的时间都花在吃东西、看电视、睡觉上面的一只大胖猫。它的主人则是一个懒散的年轻人，他还拥有一只整天只知道吐舌头和追汽车的小狗——欧第。当然，欧第就成了加菲每天玩弄的对象。这一系列的动画片就是围绕着一只肥猫、一条傻狗和一个整天迷迷糊糊的主人展开的。

In this season, the show went back to airing one new episode a week, but stayed in the hour-length format, filling up the second half-hour with episodes from previous seasons and some of the prime-time specials from the 1980s. This entire season, along with the second half of season 6, is available on Garfield and Friends Volume 5 DVD set. Also worth noting is that here, a new theme song was added that was written by J.R. Johnston and Neil Panton. The theme was sung by J.R. Johnston. This theme song was not shown internationally, and as a result, it does not appear on the DVDs (although Garfield's quotations are kept intact). This new introduction sequence used most clips from Seasons 5-7 and a few from the first two seasons, as well as Garfield in Paradise and Garfield's Feline Fantasies. The episodes stopped using a few seconds of the theme playing in the episode title cards after season seven's fourth episode; music from the episodes were used in the title cards until the show ended, even though season six used music from some of their episodes.

Skyway Robbery Jon, Garfield and Odie are passengers on a rickety broken-down plane flown by Al G. Swindler, who bails out and leaves them to fly the plane. The Bunny Rabbits is Coming! Orson and the others receive a moxia.cc telegram that says only 'The bunny rabbits is coming'. Close Encounters of the Garfield Kind John, Garfield and Odie encounter a cute little alien whose reasons for coming to earth are more sinister than he leads them to believe.

《加菲猫和他的朋友们第二季》是一部由Jeff HallTom Ray、Ron Myrick执导，Lorenzo Music等主演的动画片，1989年9月17日在美国首播。

懒惰却又聪明的肥猫、又笨又可爱的傻狗和一个整天迷迷糊糊的主人乔恩之间的搞笑日常故事。

In honor to celebrate the 15th anniversary of Garfield, CBS aired the sixth season in 1993. For this season, the titles changed at the beginning. Instead of showing clips from only the first two seasons, which is what happened for the last three seasons, the titles included more clips from the fifth season, plus some from this season and one from a second season episode Health Feud, but still retaining a large amount of the original clips. However, the theme tune remained the same. Episodes 90–96 are available on the Garfield and Friends Volume 4 DVD set. Episodes 97–105 are available on Garfield and Friends Volume 5 DVD set.

《加菲猫的幸福生活 第五季》，讲述一段不平凡的“猫鼠大战”。乔恩坚信只要有加菲猫在，就可以保证家里没有老鼠，但实际上情况并非如此，表面平静的家其实人员众多，热闹非凡…… 老鼠小吱要出走几天，所以他让这个不太聪明的小弟—阿文看管家里。结果小吱离开不久，惹是生非的表哥鼠仔就出现了。

全身长着橙色皮毛的加菲猫是一只生长在大都会内一个平凡街区的猫儿，他天生具有哲人般的怪想法和似乎有无止境的旺盛食欲。比萨、猪肉卷、意大利面、蛋糕乃至各种无上美味且具含高热量高脂肪的食物都是加菲的最爱，而对于青菜、老鼠等等则嗤之以鼻。对他来说，美美的吃上一顿后再打个盹，这便是最完美的猫生。而那个身为漫画家的主人乔恩，毋宁说是老天专门派来服侍他的仆人；小狗欧弟则当仁不让是加菲解闷找乐的首选对象。加菲猫自私、小气、贪婪、懒惰、虚荣、自恋，可是却得到了全世界的宠爱……　　本片根据吉姆·戴维斯（Jim Davis）的同名漫画作品改编。